A UNIQUE SOLUTION

for breast pain, sensitivity and sagging!

BRESIVA KREM
Bresiva krem za grudi
90 %

DEVELOPED IN COLLABORATION WITH MEDICAL EXPERTS

BRESIVA KREM

Mastalgia (mamalgia, mastodynia) is characterized by pain and tension in the breasts and can be classified as cyclical and non-cyclical. Cyclic mastalgia: this type of breast pain is associated with the menstrual cycle – it occurs in women between the ages of 20 and 50. Cyclic mastalgia is almost always bilateral, diffuse and correlated with the luteal phase of the menstrual cycle. The pain occurs due to natural hormonal changes, about a week before menstruation. Initially a weaker pain occurs in the upper outer parts of the chest that disappears spontaneously when menstruation occurs. It does not require further examination and is treated symptomatically (NSAIDs orally and locally).

Non-cyclical mastalgia: This type of breast pain is not related to the menstrual cycle and is more common in women between 40 and 50 years of age. Non-cyclical mastalgia is most often focal – it affects only one breast, usually in one smaller portion of the breast, but it can also spread. Pain can be continuous or sporadic. Non-cyclical mastalgia can be associated with the use of certain drugs, infection, inflammation, the presence of cysts or fibroadenomas, costochondritis, the presence of scar tissue (post-operative), larger breasts. Non-cyclical pain can also occur due to smoking, caffeine consumption, physical or emotional stress, breastfeeding, lack of essential fatty acids (such as linolenic acid) or iodine deficiency.

In many cases, there is no obvious cause of breast pain, and pain is usually not a symptom of breast cancer.

Patients most often describe breast pain as a heavy, dull pain, but also as a pain similar to a stabbing or as a burning sensation.

krerm-en
  • Cabbage leaf extract has, in several studies, shown a positive effect in alleviating tension, heaviness and pain in the breasts, and is traditionally known for its beneficial effect on swelling and inflammatory conditions.
  • Edelweiss stem cell extract (lat. Leontopodium Alpinum Callus Culture Extract) has, in several studies, shown a positive effect with regard to skin firmness, as well as exhibiting a lifting effect – it is ideal for skin that lacks tone and firmness. Thanks to its exceptional antioxidant potential, Edelweiss stem cell extract restores skin firmness by regenerating mitochondrial dynamism and protecting the integrity of the extracellular matrix. Edelweiss extract is the subject of numerous studies due to its high content of leontopodic acid and other phenolic compounds that show a high level of anti-inflammatory and antioxidant activity. As a result of topical application of Edelweiss stem cell extract, there is a visible tightening and lifting of the skin of the breasts.
  • Fenugreek extract improves hydration of the skin as well as its elasticity and firmness due to it possessing numerous bioactive compounds, especially flavonoids (rutin, quercetin, vitexin) and alkaloids. Also, fenugreek possesses antioxidant and soothing effects.
  • Wintergreen essential oil reduces discomfort and tension in the chest, providing a pleasant cooling sensation. The main ingredient of wintergreen essential oil is methyl salicylate, a derivative of salicylic acid, which can act like salicylate analgoantipyretics, i.e. using the same mechanism to influence inflammatory processes in tissues and reduce painful sensations.
  • Precious raspberry and cotton seed oils are rich in essential fatty acids and vitamins. They intensely nourish and revitalize the skin, leaving it soft and smooth.
  • BRESIVA Breast Cream’s complex formulation contributes to the reduction of sweating at the site of application, as it contains sodium hydrogen carbonate that absorbs excess liquid and prevents the occurrence of unpleasant odours. Due to this fact, the occurrence of skin irritations caused by sweating is also reduced.
Bresiva krem za grudi

REVOLUTIONARY BREAST CREAM WITH TRIPLE ACTION

SOOTHES

It reduces sensitivity, tension and the feeling of heaviness in the breasts

FIRMS

Increases the tone and firmness of the breasts

REVITALIZES

The skin of the breasts and reduces sweating

bedzevi-en

RECOMMENDATIONS

  • Wear comfortable bras
  • Reduce your caffeine intake
  • Avoid smoking
  • Partake in a diet with fewer fats and more complex carbohydrates
  • Avoid lifting heavy loads

EXPERT ADVICE

In order to detect various breast diseases early, the following are necessary:

  • Regular annual examinations by an oncological surgeon after the age of 25.
  • Annual breast ultrasound examination after the age of 25.
  • Mammography after the age of 45.
  • Breast self-examination once a month

Literature and sources:
1.
Mirzaee F, Fakari FR, Babakhanian M, Roozbeh N, Ghazanfarpour M. The Effectiveness of Herbal Medicines on Cyclic Mastalgia: A Systematic Review on Meta-analysis. Rev Bras Ginecol Obstet. 2022 Oct:44(10):972-985. doi: 10.1055/s-0042 1755456. Epub 2022 Nov 29. PMID:36446563: PMCID: PMC9708400.

2. Bonilla-Sepulveda, Óscar A., & Giraldo-Santa, D. C. (2019). Mastodynia. CES Medicina, 33(2), 111- 118. https://doi.org/10.21615/c smedicina.33.2.4

3. Eaknai W, Bunwatcharaphansakun P, Phungbun C, Jantimaporn A, Chaisri S, Boonrungsiman S, Nimmannit U, Khongkow M. Ethanolic Fenugreek Extract: Its Molecular Mechanisms against Skin Aging and the Enhanced Functions by Nanoencapsulation. Pharmaceuticals (Basel). 2022 Feb 20:15(2):254. dol: 10.3390/ph15020254. PMID: 35215366: PMCID: PMC8879298.

4. Hafiz SP, Barnes NLP, Kirwan CC. Clinical management of idiopathic mastalgia: a systematic review. J Prim Health Care. 2018 Dec;10(4):312-323. doi: 10.1071/HC18026. PMID: 31039960.

5. Chobpenthai T, Arunwatthanangkul P, Mahikul W. Efficacy of Cabbage Leaf versus Cooling Gel Pad or Diclofenac Gel for Patients with Knee Osteoarthritis: A Randomized Open-Labeled Controlled Clinical Trial. Pain Res Manag. 2022 Jun 8:2022:3122153. doi: 10.1155/2022/3122153. PMID: 35719197:PMCID: PMC9200597.

6. Ansari M, Sadeghi P, Mahdavi H, Fattahi Dolatabadi M, Mohamadi N, Asadi A, Sharififar F. Fenugreek dermal patch, a new natural topical antinociceptive medication for relieving the postherniotomy pain, a double-blind placebo controlled trial. J Complement Integr Med. 2019 Feb 5:16(3):/j/jcim.2019.16.issue- 3/jcim-2018-0082/jcim 2018-0082.xml. doi: 10.1515/jcim-201- 0082. PMID: 30721143.

7. Ganzera M. Greifeneder V. Schwaiger S. Stuppner H. Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography. Fitoterapia. 2012 Dec:83(8):1680-6.

8. Daniela L. Alla P. Maurelli R. et.al. Anti inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells. Mediators of Inflammation. 2012. Article ID 498373 pp. 1-12.

9. Costa S. Schwaiger S. Cervellati R. Stuppner H. Speroni E. Guerra MC. In vitro evaluation of the chemoprotective action  mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenolinducedcell damage. J Appl Toxicol. 2009 Jan;29(1):7-14.

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